Beta Free full access during beta. All models, tools, and daily picks included.
Early Preview Lineups: Projected Odds Posted 6 min read

St. Louis Cardinals vs Pittsburgh Pirates Preview

STL at PIT 2026-09-22 preview: probable pitchers, projected lineups, NRFI/F5 model picks, weather, ballpark, and umpire context.

St. Louis Cardinals at Pittsburgh Pirates MLB game preview for September 22, 2026
STL
St. Louis Cardinals
Andre Pallante RHP
@
6:40 PM ET
PNC Park
PIT
Pittsburgh Pirates
Jared Jones RHP
Last updated Tuesday, September 22, 2026

Key Facts

Matchup
St. Louis Cardinals at Pittsburgh Pirates
Date
Tuesday, September 22, 2026
First Pitch
6:40 PM ET
Venue
PNC Park
Probable Starters
Andre Pallante (RHP) vs Jared Jones (RHP)
Lineups
Projected
Odds Snapshot
Sep 22, 6:41 PM ET
Last Updated
Sep 22, 7:26 AM ET

Betting Board

Snapshot Sep 22, 6:41 PM ET
Moneyline
STL +132
PIT -146
Total
Over 7.5 +102
Under 7.5 -124
Run Line
STL +1.5 -188
PIT -1.5 +155

Model Angles

NRFI Model
NRFI · 57%
+7.2% edge · playable
Projected Total
5.4
model combined runs
Park Factor
1.00
Neutral · HR 0.98
First Pitch Weather
59°F
9.6 mph ENE
The St. Louis Cardinals visit the Pittsburgh Pirates at 6:40 PM ET at PNC Park. Probable starters: Andre Pallante for St. Louis Cardinals opposite Jared Jones for Pittsburgh Pirates. Lineups are projected until first pitch. This preview is built deterministically from projected lineups, probable starters, NRFI model context, market prices, first-pitch weather, park factors, and TheCapperIO model context.
  • Starter matchup: Andre Pallante (St. Louis Cardinals) vs Jared Jones (Pittsburgh Pirates).
  • Lineup status: projected until official release.
  • NRFI model: 57% probability, lean NRFI, +7.2% edge.

Pitching Matchup

STL Away
Andre Pallante
RHP · 12-7 · 27 GS
ERA
3.70
WHIP
1.26
K/9
6.20
IP
151.0
Career: 4.17 ERA · 1.38 WHIP · 6.26 K/9
NRFI: 70.0%
1st Inn ERA: 5.31
PIT Home
Jared Jones
RHP · 4-6 · 19 GS
ERA
4.17
WHIP
1.19
K/9
10.82
IP
90.2
Career: 4.15 ERA · 1.19 WHIP · 10.22 K/9
NRFI: 83.2%
1st Inn ERA: 2.20

On the season, Andre Pallante holds the ERA edge in this matchup. Andre Pallante carries a 3.70 ERA and 1.26 WHIP, while Jared Jones sits at 4.17 ERA and 1.19 WHIP.
Strikeout rates: Andre Pallante at 6.20 K/9, Jared Jones at 10.82 K/9.
K projections: Andre Pallante at 2.9 (line 3.5)
Jared Jones projected at 5.0 (line 5.5).
First-inning scoring: Andre Pallante holds a 70.0% career NRFI rate, Jared Jones at 83.2%. Combined average: 76.6%.
Both starters throw from the R side, limiting platoon splits for either lineup.

Strikeout Projections

Andre Pallante vs PIT
Proj: 2.9Line: 3.5
-0.6
Confidence:
Jared Jones vs STL
Proj: 5.0Line: 5.5
-0.5
Confidence:
View all K projections on SlateIQ

Our strikeout model weighs pitcher K rate, opponent lineup whiff tendency, park factors, and umpire zone size to project total strikeouts per starter.

Andre Pallante (St. Louis Cardinals) is projected for 2.9 strikeouts against a posted line of 3.5. The projection is close to the line with no actionable edge.
He faces a high-K lineup that strikes out at 24.2% with a 28.0% whiff rate.

Jared Jones (Pittsburgh Pirates) is projected for 5.0 strikeouts against a posted line of 5.5. The projection is close to the line with no actionable edge.
He faces a moderate-K lineup that strikes out at 23.1% with a 28.0% whiff rate.

The Pittsburgh Pirates lineup is more vulnerable to strikeouts in this matchup. Pittsburgh Pirates batters K at 24.2%, St. Louis Cardinals batters at 23.1%.

NRFI & First 5 Analysis

NRFI Model
56.7%
probability of NRFI
+7.2%
market edge
Signal
Market implied: 49.5%Model: 56.7%
First 5 Innings
3.0est. F5 runs
STL
3.70 ERA
5.6 inn/start
PIT
4.17 ERA
4.7 inn/start
F5 lean: Even matchup
STL K Projection
Andre Pallante
2.9proj
Line: 3.5
-0.6 NEUTRAL
Confidence
PIT K Projection
Jared Jones
5.0proj
Line: 5.5
-0.5 NEUTRAL
Confidence
Explore all model projections

Our NRFI model analyzes both starting pitchers' first-inning profiles, the top-of-order hitters in each lineup, the umpire's historical zone, and environmental factors to produce a probability estimate. For this game, the model assigns a 56.7% probability of no runs in the first inning, compared to the market's implied probability of 49.5%.

  • That creates a moderate 7.2% edge on NRFI.
  • The best available line is NRFI +102 / YRFI -124 at FanDuel.
  • This qualifies as a playable in our publication system.

The home plate umpire for this game has not yet been assigned. MLB typically posts assignments the morning of game day. Umpire data will be added automatically once the assignment is posted.
Our NRFI model sits at 159-154 (50.8%) on official picks this season.

Lineup & Matchup Breakdown

St. Louis Cardinals Projected
K%: 23.1
Whiff rate: 28.0%Team page
Pittsburgh Pirates Projected
K%: 24.2
Whiff rate: 28.0%Team page
Batter vs Pitcher matchup tool

Lineups are projected as of this writing.

St. Louis Cardinals K vulnerability: 23.1% strikeout rate, 28.0% whiff rate.

Pittsburgh Pirates K vulnerability: 24.2% strikeout rate, 28.0% whiff rate.

Ballpark, Weather & Umpire

PNC Park
Run Factor1.00
HR Factor0.98
Full park profile
Hourly Game Forecast
59°
6 PM
10 mph
ENE
57°
7 PM
9 mph
ENE
57°
8 PM
9 mph
ENE
57°
9 PM
9 mph
ENE
  • PNC Park carries a 1.00 run factor (neutral).
  • Home run factor: 0.98 — the park neutral for HR power.
  • Park notes: Right field wall angles; Elevated RF corner; Allegheny River backdrop.
  • First pitch forecast: 58F with 10 mph winds from the ENE. Humidity: 84%.
  • Wind advisory: 10 mph winds from the ENE may impact fly balls.

Home plate umpire: Not yet assigned. Umpire data will be added once the assignment is posted.

Run Projections & Total

  • Our projection model puts the total at 5.4 combined runs, with St. Louis Cardinals projected for 2.6 and Pittsburgh Pirates for 2.8.
  • That's 2.1 runs below the posted total of 7.5, suggesting a lean toward the Under.
  • The run projection is essentially a coin flip between these two teams.
The Bottom Line
This is a data-first preview, not a pick. Treat the NRFI model signal as context alongside the pitching matchup. Verify current odds before placing any bet. Confirm lineups at first pitch. Bet responsibly. 1-800-GAMBLER.
This preview is generated from thecapper.io projection models and publicly available data. All projections are model estimates, not guarantees. Gamble responsibly. If you or someone you know has a gambling problem, call 1-800-GAMBLER.