Beta Free full access during beta. All models, tools, and daily picks included.
Game-Day Update Lineups: Projected Odds Pending 5 min read

St. Louis Cardinals vs Milwaukee Brewers Preview

STL at MIL 2026-09-26 preview: probable pitchers, projected lineups, NRFI/F5 model picks, weather, ballpark, and umpire context.

St. Louis Cardinals at Milwaukee Brewers MLB game preview for September 26, 2026
STL
St. Louis Cardinals
Quinn Mathews LHP
@
7:10 PM ET
American Family Field
MIL
Milwaukee Brewers
Dustin May RHP
Last updated Saturday, September 26, 2026

Key Facts

Matchup
St. Louis Cardinals at Milwaukee Brewers
Date
Saturday, September 26, 2026
First Pitch
7:10 PM ET
Venue
American Family Field
Probable Starters
Quinn Mathews (LHP) vs Dustin May (RHP)
Lineups
Projected
Last Updated
Sep 26, 12:22 AM ET

Betting Board

Lines not yet posted
Sportsbooks have not published markets for this matchup yet. Check back closer to first pitch, or see today's model-backed picks for games with live odds.

Model Angles

NRFI Model
Not yet available
Projected Total
TBD
Park Factor
0.98
Neutral · HR 1.06
First Pitch Weather
Roof
Climate controlled
The St. Louis Cardinals visit the Milwaukee Brewers at 7:10 PM ET at American Family Field. Probable starters: Quinn Mathews for St. Louis Cardinals opposite Dustin May for Milwaukee Brewers. Lineups are projected until first pitch. This preview is built deterministically from projected lineups, probable starters, odds where available, a roofed ballpark note, park factors, and TheCapperIO model context.
  • Starter matchup: Quinn Mathews (St. Louis Cardinals) vs Dustin May (Milwaukee Brewers).
  • Lineup status: projected until official release.
  • Park factor: 0.98 runs; venue American Family Field.

Pitching Matchup

STL Away
Quinn Mathews
LHP · 2-3 · 8 GS
ERA
3.65
WHIP
1.38
K/9
7.92
IP
44.1
Career: 3.65 ERA · 1.38 WHIP · 7.92 K/9
MIL Home
Dustin May
RHP · 7-9 · 30 GS
ERA
4.67
WHIP
1.32
K/9
8.77
IP
142.2
Career: 4.11 ERA · 1.24 WHIP · 8.41 K/9
NRFI: 66.0%
1st Inn ERA: 5.71

On the season, Quinn Mathews holds the ERA edge in this matchup. Quinn Mathews carries a 3.65 ERA and 1.38 WHIP, while Dustin May sits at 4.67 ERA and 1.32 WHIP.
Strikeout rates: Quinn Mathews at 7.92 K/9, Dustin May at 8.77 K/9.
K projections: Quinn Mathews at 3.8 (line 4.0)
Dustin May projected at 3.5 (line 4.0).
Dustin May has a 66.0% career NRFI rate. No first-inning data available for Quinn Mathews.
This is a LHP vs RHP matchup, creating potential platoon advantages in both lineups.

Strikeout Projections

Quinn Mathews vs MIL
Proj: 3.8Line: 4.0
-0.2
Confidence:
Dustin May vs STL
Proj: 3.5Line: 4.0
-0.5
Confidence:
View all K projections on SlateIQ

Our strikeout model weighs pitcher K rate, opponent lineup whiff tendency, park factors, and umpire zone size to project total strikeouts per starter.

Quinn Mathews (St. Louis Cardinals) is projected for 3.8 strikeouts against a posted line of 4.0. The projection is close to the line with no actionable edge.
He faces a high-K lineup that strikes out at 24.8% with a 28.0% whiff rate.

Dustin May (Milwaukee Brewers) is projected for 3.5 strikeouts against a posted line of 4.0. The projection is close to the line with no actionable edge.
He faces a high-K lineup that strikes out at 24.2% with a 28.0% whiff rate.

The Milwaukee Brewers lineup is more vulnerable to strikeouts in this matchup. Milwaukee Brewers batters K at 24.8%, St. Louis Cardinals batters at 24.2%.

Prop Edges

1 model signal detected
Hits (1+) Lean Hit 0.5
69.9%
See all today's picks and edges

Lineup & Matchup Breakdown

St. Louis Cardinals Projected
K%: 24.2
Whiff rate: 28.0%Team page
Milwaukee Brewers Projected
K%: 24.8
3William ContrerasRC
Whiff rate: 28.0%Team page
Batter vs Pitcher matchup tool

Lineups are projected as of this writing.

St. Louis Cardinals K vulnerability: 24.2% strikeout rate, 28.0% whiff rate.

Milwaukee Brewers K vulnerability: 24.8% strikeout rate, 28.0% whiff rate.

Ballpark, Weather & Umpire

American Family Field
Run Factor0.98
HR Factor1.06
Full park profile
  • American Family Field carries a 0.98 run factor (neutral).
  • Home run factor: 1.06 — the park elevates HR power.
  • Park notes: 6th easiest HR but 26th in runs; Elevated position; Retractable roof.
  • Roof: Retractable.

Climate controlled. Roof expected closed. Standard 72F conditions, no wind factor.

Home plate umpire: Not yet assigned. Umpire data will be added once the assignment is posted.

Run Projections & Total

Run projections not available for this game.

The Bottom Line
This is a data-first preview, not a pick. Check final odds once sportsbooks post markets. Confirm lineups at first pitch. Bet responsibly. 1-800-GAMBLER.
This preview is generated from thecapper.io projection models and publicly available data. All projections are model estimates, not guarantees. Gamble responsibly. If you or someone you know has a gambling problem, call 1-800-GAMBLER.